Cities Similar to St. Louis, MO

The top 10 most similar cities based on cost of living, home prices, rent, population, and region.

Cities similar to St. Louis, MO

1. St. Paul, MN

303,820 people · Midwest

100% similar

COL Index

N/A

Home Price

N/A

Rent

N/A

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2. Toledo, OH

265,304 people · Midwest

99% similar

COL Index

N/A

Home Price

$130K

Rent

N/A

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3. Cincinnati, OH

309,317 people · Midwest

99% similar

COL Index

89.0

Home Price

$225K

Rent

$780/mo

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4. Sioux Falls, SD

206,410 people · Midwest

98% similar

COL Index

N/A

Home Price

$280K

Rent

N/A

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5. Wichita, KS

396,119 people · Midwest

98% similar

COL Index

86.0

Home Price

$202K

Rent

$650/mo

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6. Grand Rapids, MI

196,608 people · Midwest

98% similar

COL Index

N/A

Home Price

$288K

Rent

N/A

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7. Akron, OH

188,701 people · Midwest

98% similar

COL Index

N/A

Home Price

$113K

Rent

N/A

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8. Lincoln, NE

295,178 people · Midwest

98% similar

COL Index

91.0

Home Price

$274K

Rent

$800/mo

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9. Overland Park, KS

197,089 people · Midwest

98% similar

COL Index

N/A

Home Price

$344K

Rent

N/A

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10. Fort Wayne, IN

270,402 people · Midwest

98% similar

COL Index

83.0

Home Price

$206K

Rent

$660/mo

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How We Find Cities Similar to St. Louis

Our similarity algorithm compares St. Louis, MO against every other city in our database across multiple dimensions: cost of living index, median home price, average rent, population size, and geographic region. Each factor is weighted and normalized, then combined into a single similarity score from 0–100%.

Cities with high similarity scores share a comparable financial profile to St. Louis — meaning your dollar goes about as far, housing costs are in the same ballpark, and the overall lifestyle cost is similar. This is useful if you love St. Louis but want to explore other options with a similar feel and price point, or if you’re relocating and want to understand which cities offer a comparable standard of living.

Click on any city in the results to see a detailed cost of living comparison, including category-by-category breakdowns for housing, groceries, transportation, healthcare, and more. You can also adjust the search to find cities similar to any location in the United States.